Dennis Ruff, MD

Medical Director

Dr. Ruff combines education in biology and internal medicine with more than 30 years of medical practice and clinical research experience with focused expertise in early phase study design, and medical safety oversight of all trial study stages.   Dr. Ruff has served as Principal Investigator or Sub-Investigator for >400 phase I-IV studies including maximum tolerated dose studies, first in human, single, and multiple ascending dose, proof of concept programs for new chemical entities, biologics and vaccines. As the Medical Director of ICON plc 120 bed phase I unit facility in San Antonio TX he was responsible for the overall coordination and execution of medical center operations, as well as conducting clinical research in accordance with FDA regulations,  and with strict adherence to clinical protocols, data integrity , and protection of the rights and welfare of the subjects under his charge.